Endocrine Abstracts

A previously well 54 year old man, with no atherosclerotic risk factors, presented with a 10 month history of claudication. Arteriography showed extensive distal aortic and iliac stenoses.At surgery, (Aortoiliac and femoral bypass) extensive thrombus was found in the distal aorta. Post operatively good distal flow was confirmed. He was discharged on Aspirin.Fourteen days later the patient was readmitted hypotensive, pyrexic, with ...

Serum gastrin (G) levels >1000 pg usually raise the suspicion for a neuroendocrine tumor (NET) secreting G. Rarely, such elevated G levels are seen in pts with pernicious anemia (PA) which most commonly is associated with autoimmune gastritis (AG) (1). AG can occur concomitantly with other autoimmune d/o incl. lymphocytic colitis (LC) (2). G stimulates enterochromaffin-like cells which increase histamine (H) secretion. H excess can cause diarrhea (D) as can bacterial overg...

Hyponatraemia is a common biochemical abnormality associated with significant mortality. However, adequate investigation and accurate diagnosis are frequently lacking. We have evaluated the assessment and management of severe hyponatraemia in a large teaching hospital. Inpatients with a plasma sodium (pNa) <125mmol/L were identified prospectively by laboratory database, over a 6 month period. Notes were examined and data extracted. Data was also retrospectively reviewed by ...